Česká Genetická Banka

In research that Science's editors chose as a runner-up for Breakthrough of the Year, scientists coaxed cells called pluripotent stem cells to grow into tiny "organoids"—liver buds, mini-kidneys, and even rudimentary human brains—in the lab. .. více zde >

"Mouse embryonic stem (ES) cells are isolated from the inner cell mass of blastocysts, and can be preserved in vitro in a naive inner-cell-mass-like configuration by providing exogenous stimulation with leukaemia inhibitory factor (LIF) and small molecule inhibition of ERK1/ERK2 and GSK3β signalling (termed 2i/LIF conditions). (...)" více zde >

"A longstanding endeavor to define the genetic lesions that drive myeloid malignances has stimulated a period of remarkable discovery. (...)" více zde >

"Many organs with a high cell turnover (for example, skin, intestine and blood) are composed of short-lived cells that require continuous replenishment by somatic stem cells. (...)" více zde >

"A fundamental enigma in modern biology concerns the molecular rules that govern how cells establish and maintain identity during development. These rules are the key to generating therapeutic cell types in vitro and the foundation of regenerative medicine." více zde >

"The report of the so-called Berlin patient cured of HIV with hematopoietic stem cell transplantation and a few other studies raised tremendous hope, excitement, and curiosity in the field. (...)" více zde >

"Cell cycle quiescence is a critical feature contributing to haematopoietic stem cell (HSC) maintenance. (...)" více zde >