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17. 06. 2013
NATURE: 13. 6. 2013
"In the push to match medical therapies to the genetic underpinnings of disease, lung-cancer treatments have been at the frontier. (...)" více zde > -
10. 06. 2013
NATURE: 6. 6. 2013
"It is a paradox that bedevils genomic medicine: despite near-universal agreement that doctors and geneticists should exchange more data, there has been scant movement towards achieving this goal. (...)" více zde > -
03. 06. 2013
SCIENCE: 31. 5. 2013
"The Italian Parliament has decided that the administration of a controversial stem cell treatment for neurodegenerative diseases, provided by the Stamina Foundation in Turin, can continue—although on only a small scale. (...)" více zde > -
27. 05. 2013
SCIENCE: 27. 5. 2013
"State-of-the-art DNA sequencing is providing ever more detailed insights into the genomes of humans, extant apes, and even extinct hominins (1–3), offering unprecedented opportunities to uncover the molecular variants that make us human. (...)" více zde > -
20. 05. 2013
SCIENCE: 20. 5. 2013
"The rapid expansion of high-through-put DNA sequencing now enables the genetic analysis of human diseases at an unprecedented rate and resolution. In particular, whole-genome sequencing of rare childhood diseases promises fundamental insight into basic developmental processes and biochemical pathways. (...)" více zde > -
13. 05. 2013
SCIENCE: 10. 5. 2013
"The cost of bringing a drug to market is staggering (estimated at more than 1 billion dollars) and the failure rate is daunting: Only one in three drugs that reach phase 3 clinical trials ultimately reach the marketplace. (...)" více zde > -
06. 05. 2013
CELL STEM CELL: 2. 5. 2013
"Embryonic stem cell (ESC) pluripotency is governed by a gene regulatory network centered on the transcription factors Oct4 and Nanog. To date, robust self-renewing ESC states have only been obtained through the chemical inhibition of signaling pathways or enforced transgene expression. (...)" více zde > -
29. 04. 2013
SCIENCE: 29. 4. 2013
When Early Hominins Got a Grip Paleoanthropologists announced a modern feature in a rare, 1.4-million-year-old hand bone from Kenya, filling a 1-million-year gap in the fossil record and showing when key adaptations to toolmaking arose. více zde >
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